diff --git a/builtin/logical/database/backend_test.go b/builtin/logical/database/backend_test.go
index 6d42fcbfd6..447ab7d66a 100644
--- a/builtin/logical/database/backend_test.go
+++ b/builtin/logical/database/backend_test.go
@@ -47,8 +47,11 @@ func getCluster(t *testing.T) (*vault.TestCluster, logical.SystemView) {
 
 	sys := vault.TestDynamicSystemView(cores[0].Core, nil)
 	vault.TestAddTestPlugin(t, cores[0].Core, "postgresql-database-plugin", consts.PluginTypeDatabase, "TestBackend_PluginMain_Postgres", []string{}, "")
+	vault.TestAddTestPlugin(t, cores[0].Core, "postgresql-database-plugin-muxed", consts.PluginTypeDatabase, "TestBackend_PluginMain_PostgresMultiplexed", []string{}, "")
 	vault.TestAddTestPlugin(t, cores[0].Core, "mongodb-database-plugin", consts.PluginTypeDatabase, "TestBackend_PluginMain_Mongo", []string{}, "")
+	vault.TestAddTestPlugin(t, cores[0].Core, "mongodb-database-plugin-muxed", consts.PluginTypeDatabase, "TestBackend_PluginMain_MongoMultiplexed", []string{}, "")
 	vault.TestAddTestPlugin(t, cores[0].Core, "mongodbatlas-database-plugin", consts.PluginTypeDatabase, "TestBackend_PluginMain_MongoAtlas", []string{}, "")
+	vault.TestAddTestPlugin(t, cores[0].Core, "mongodbatlas-database-plugin-muxed", consts.PluginTypeDatabase, "TestBackend_PluginMain_MongoAtlasMultiplexed", []string{}, "")
 
 	return cluster, sys
 }
@@ -66,6 +69,14 @@ func TestBackend_PluginMain_Postgres(t *testing.T) {
 	v5.Serve(dbType.(v5.Database))
 }
 
+func TestBackend_PluginMain_PostgresMultiplexed(t *testing.T) {
+	if os.Getenv(pluginutil.PluginVaultVersionEnv) == "" {
+		return
+	}
+
+	v5.ServeMultiplex(postgresql.New)
+}
+
 func TestBackend_PluginMain_Mongo(t *testing.T) {
 	if os.Getenv(pluginutil.PluginVaultVersionEnv) == "" {
 		return
@@ -79,6 +90,14 @@ func TestBackend_PluginMain_Mongo(t *testing.T) {
 	v5.Serve(dbType.(v5.Database))
 }
 
+func TestBackend_PluginMain_MongoMultiplexed(t *testing.T) {
+	if os.Getenv(pluginutil.PluginVaultVersionEnv) == "" {
+		return
+	}
+
+	v5.ServeMultiplex(mongodb.New)
+}
+
 func TestBackend_PluginMain_MongoAtlas(t *testing.T) {
 	if os.Getenv(pluginutil.PluginUnwrapTokenEnv) == "" {
 		return
@@ -92,6 +111,14 @@ func TestBackend_PluginMain_MongoAtlas(t *testing.T) {
 	v5.Serve(dbType.(v5.Database))
 }
 
+func TestBackend_PluginMain_MongoAtlasMultiplexed(t *testing.T) {
+	if os.Getenv(pluginutil.PluginUnwrapTokenEnv) == "" {
+		return
+	}
+
+	v5.ServeMultiplex(mongodbatlas.New)
+}
+
 func TestBackend_RoleUpgrade(t *testing.T) {
 	storage := &logical.InmemStorage{}
 	backend := &databaseBackend{}
diff --git a/builtin/logical/database/mockv5.go b/builtin/logical/database/mockv5.go
index 84db3eb196..632cfb38e0 100644
--- a/builtin/logical/database/mockv5.go
+++ b/builtin/logical/database/mockv5.go
@@ -36,6 +36,13 @@ func RunV5() error {
 	return nil
 }
 
+// Run instantiates a MongoDB object, and runs the RPC server for the plugin
+func RunV6Multiplexed() error {
+	v5.ServeMultiplex(New)
+
+	return nil
+}
+
 func (m MockDatabaseV5) Initialize(ctx context.Context, req v5.InitializeRequest) (v5.InitializeResponse, error) {
 	log.Default().Info("Initialize called",
 		"req", req)
diff --git a/builtin/logical/database/versioning_large_test.go b/builtin/logical/database/versioning_large_test.go
index db29413085..723f9dd808 100644
--- a/builtin/logical/database/versioning_large_test.go
+++ b/builtin/logical/database/versioning_large_test.go
@@ -24,6 +24,7 @@ func TestPlugin_lifecycle(t *testing.T) {
 
 	vault.TestAddTestPlugin(t, cluster.Cores[0].Core, "mock-v4-database-plugin", consts.PluginTypeDatabase, "TestBackend_PluginMain_MockV4", []string{}, "")
 	vault.TestAddTestPlugin(t, cluster.Cores[0].Core, "mock-v5-database-plugin", consts.PluginTypeDatabase, "TestBackend_PluginMain_MockV5", []string{}, "")
+	vault.TestAddTestPlugin(t, cluster.Cores[0].Core, "mock-v6-database-plugin-muxed", consts.PluginTypeDatabase, "TestBackend_PluginMain_MockV6Multiplexed", []string{}, "")
 
 	config := logical.TestBackendConfig()
 	config.StorageView = &logical.InmemStorage{}
@@ -261,6 +262,14 @@ func TestBackend_PluginMain_MockV5(t *testing.T) {
 	RunV5()
 }
 
+func TestBackend_PluginMain_MockV6Multiplexed(t *testing.T) {
+	if os.Getenv(pluginutil.PluginVaultVersionEnv) == "" {
+		return
+	}
+
+	RunV6Multiplexed()
+}
+
 func assertNoRespData(t *testing.T, resp *logical.Response) {
 	t.Helper()
 	if resp != nil && len(resp.Data) > 0 {